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Masayuki Kuroda Selected Research

Lecithin Cholesterol Acyltransferase Deficiency (Lecithin:Cholesterol Acyltransferase Deficiency)

8/2022LCAT-trial-24 weeks: Protocol for a clinical study to evaluate the safety of regenerative medicine and gene therapy by the autologous transplantation of human lecithin:cholesterol acyltransferase gene-transduced human pre-adipocytes.
7/2021Current Status of Familial LCAT Deficiency in Japan.
1/2020Esterification of 4β-hydroxycholesterol and other oxysterols in human plasma occurs independently of LCAT.
7/2018Immune-mediated acquired lecithin-cholesterol acyltransferase deficiency: A case report and literature review.
11/2016A case of acquired lecithin:cholesterol acyltransferase deficiency with sarcoidosis that remitted spontaneously.
1/2016Gene-manipulated Adipocytes for the Treatment of Various Intractable Diseases.
8/2014Lipoprotein subfractions highly associated with renal damage in familial lecithin:cholesterol acyltransferase deficiency.
5/2013Amelioration of circulating lipoprotein profile and proteinuria in a patient with LCAT deficiency due to a novel mutation (Cys74Tyr) in the lid region of LCAT under a fat-restricted diet and ARB treatment.
3/2011Fibrin glue increases the cell survival and the transduced gene product secretion of the ceiling culture-derived adipocytes transplanted in mice.
2/2011Disturbed apolipoprotein A-I-containing lipoproteins in fish-eye disease are improved by the lecithin:cholesterol acyltransferase produced by gene-transduced adipocytes in vitro.

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Masayuki Kuroda Research Topics

Disease

10Lecithin Cholesterol Acyltransferase Deficiency (Lecithin:Cholesterol Acyltransferase Deficiency)
08/2022 - 02/2011
3Corneal Opacity
07/2022 - 05/2013
2Anemia
07/2021 - 05/2013
2Renal Insufficiency (Renal Failure)
07/2021 - 08/2014
2Proteinuria
07/2021 - 05/2013
2Breast Neoplasms (Breast Cancer)
04/2020 - 04/2015
2Neoplasms (Cancer)
04/2015 - 12/2005
2Lymphoma (Lymphomas)
06/2007 - 05/2005
2Epstein-Barr Virus Infections
05/2005 - 04/2004
1Rare Diseases (Rare Disease)
08/2022
1Nephrotic Syndrome (Syndrome, Nephrotic)
07/2018
1Myelitis
01/2017
1Congenital Abnormalities (Deformity)
06/2016
1Hemophilia A (Haemophilia)
01/2016
1Hypoxia (Hypoxemia)
08/2015
1Muscular Diseases (Myopathy)
01/2015
1Frontotemporal Dementia (Semantic Dementia)
01/2015
1Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
01/2015
1Amyloid Plaque
10/2013
1Inborn Genetic Diseases (Disease, Hereditary)
05/2013
1Starvation
05/2012
1Metabolic Diseases (Metabolic Disease)
10/2011
1Burkitt Lymphoma (Burkitt's Lymphoma)
06/2007
1Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse)
06/2007
1Communicable Diseases (Infectious Diseases)
10/2005
1B-Cell Lymphoma (Lymphoma, B Cell)
05/2005

Drug/Important Bio-Agent (IBA)

7Phosphatidylcholine-Sterol O-Acyltransferase (Lecithin Cholesterol Acyltransferase)IBA
08/2022 - 02/2011
5Lipoproteins (Lipoprotein)IBA
07/2021 - 02/2011
3Proteins (Proteins, Gene)FDA Link
07/2022 - 03/2011
3HDL CholesterolIBA
07/2022 - 11/2016
2LipidsIBA
07/2022 - 05/2013
2Apolipoprotein A-I (Apolipoprotein A1)IBA
07/2022 - 02/2011
2EnzymesIBA
07/2021 - 02/2011
2AntibodiesIBA
04/2020 - 11/2016
1Apolipoproteins B (ApoB)IBA
07/2021
1Trastuzumab (Herceptin)FDA Link
04/2020
1CholesterolIBA
01/2020
1SterolsIBA
01/2020
1Immunoglobulin E (IgE)IBA
01/2017
1Immunoglobulin G (IgG)IBA
11/2016
1Blood Proteins (Serum Proteins)IBA
01/2016
1Recombinant ProteinsIBA
01/2016
1Interleukin-6 (Interleukin 6)IBA
04/2015
1AdipokinesIBA
04/2015
1CollagenIBA
04/2015
1GelsIBA
04/2015
1Amino AcidsFDA Link
01/2015
1Valosin Containing ProteinIBA
01/2015
1Amyloid (Amyloid Fibrils)IBA
10/2013
1Angiotensin Receptor AntagonistsIBA
05/2013
1Cycloheximide (Cicloheximide)IBA
05/2012
1FibrinIBA
03/2011
1Biological ProductsIBA
06/2007
1Bone Morphogenetic Protein 6IBA
06/2007
1N-Acetylmuramoyl-L-alanine Amidase (Autolysin)IBA
10/2005
1Rituximab (Mabthera)FDA Link
05/2005
1Ganciclovir (Cytovene)FDA LinkGeneric
05/2005
1Dexamethasone (Maxidex)FDA LinkGeneric
05/2005
1Viral ProteinsIBA
04/2004

Therapy/Procedure

7Therapeutics
07/2021 - 05/2005
1Cell- and Tissue-Based Therapy (Cell Therapy)
08/2022
1Renal Dialysis (Hemodialysis)
07/2021
1Vertebroplasty
06/2016
1Transplantation
08/2015
1Mastectomy (Mammectomy)
04/2015
1Fat-Restricted Diet (Diet, Fat Restricted)
05/2013
1Phage Therapy
10/2005